Much of ETC's work focuses on controlling antibiotic use. Any use of antibiotics, whether appropriate or not, diminishes antibiotic effectiveness. We can ask doctors to prescribe fewer antibiotics and ask patients not to demand them. We can do our utmost to control infection, but sometimes we still need antibiotics. In these cases novel treatment strategies can prolong the usefulness of a drug. These strategies include shifting away from broad-spectrum antibiotics and toward narrow spectrum antibiotics, rotating or cycling antibiotics, and using multiple first line therapies. These approaches along with other novel therapies are being evaluated.