Using Oral Vancomycin Prescriptions as a Proxy Measure for Clostridium difficile Infections

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Sales for a drug may be correlated with the prevalence of a condition treated by the drug. We found that state data revealed a strong spatial association and national data a strong temporal association between Clostridium difficile and oral vancomycin prescription sales, suggesting a new “signal” for detecting disease activity.

Philip M. Polgreen
M. Yang
J. L. Kuntz
Ramanan Laxminarayan
J. E. Cavanaugh