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Creator
Marin L. Schweizer
Michael R. Eber
Ramanan Laxminarayan
Jon P. Furuno
Kyle J. Popovich
Bala Hota
Michael A. Rubin
Eli N. Perencevich
Keywords, , , ,

 The Question

Creator
Eili Y Klein
Ramanan Laxminarayan
David L Smith
Lova Sun
Keywords, , ,
“One-Size-Fits-All”?
Optimizing Treatment Duration for Bacterial Infections

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Creator
Patricia Geli
Ramanan Laxminarayan
Michael Dunne
David L. Smith
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Policy Brief 12.pdf

The health and economic burden of resistance has not escaped the attention of federal legislators, who have proposed policies to slow the emergence and spread of resistance and resistant infections in communities, health care facilities, and food-producing animals. Bills introduced during the 2009–2010 session of Congress focused on three important strategies for curbing resistance: (1) encouraging judicious antibiotic use; (2) reducing hospital infections using public reporting programs; and (3) stimulating the development of new antibiotics (Table 1).

Creator
Yolisa Nalule
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Background

Knowledge of seasonal trends in hospital-associated infection incidence may improve surveillance and help guide the design and evaluation of infection prevention interventions. We estimated seasonal variation in the frequencies of inpatient bloodstream infections (BSIs) caused by common bacterial pathogens and examined associations of monthly BSI frequencies with ambient outdoor temperature, precipitation, and humidity levels.

Creator
Michael R. Eber
Michelle Shardell
Marin L. Schweizer
Ramanan Laxminarayan
Eli N. Perencevich
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We show that respiratory fluoroquinolone use is extremely seasonal and that fluoroquinolone use is strongly associated with influenza. In our time series model, instantaneous influenza activity was a significant predictor of use ([Formula: see text]). Also, we estimated that reducing influenza activity by 20% would reduce prescriptions by 8%.

Creator
Philip M. Polgreen
M. Yang
Ramanan Laxminarayan
J. E. Cavanaugh
Keywords,

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Sales for a drug may be correlated with the prevalence of a condition treated by the drug. We found that state data revealed a strong spatial association and national data a strong temporal association between Clostridium difficile and oral vancomycin prescription sales, suggesting a new “signal” for detecting disease activity.

Creator
Philip M. Polgreen
M. Yang
J. L. Kuntz
Ramanan Laxminarayan
J. E. Cavanaugh
Keywords,
Improving Antimicrobial Stewardship
The Evolution of Programmatic Strategies and Barriers

Objective: To describe the prevalence and characteristics of antimicrobial stewardship programs (ASPs) in hospitals across the United States and to describe financial support provided for these programs.

Design:  Electronic and paper 14-question survey of infectious diseases physician members of the Infectious Diseases Society of America Emerging Infections Network (IDSA EIN). Participants. All 1,044 IDSA EIN members who care for adult patients were invited to participate.

Creator
Birgir Johannsson
Susan E. Beekmann
Arjun Srinivasan
Adam L. Hersh
Ramanan Laxminarayan
Philip M. Polgreen
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Policy Brief 11.pdf

Inappropriate antibiotic prescribing in the United States is a common problem and imposes a significant cost on society in two ways. First, it increases the rate at which bacteria that are resistant to clinically important antibiotics emerge and spread both in hospitals and the community. And second, it comes in the way of the patient being treated for the true underlying cause of disease.

Creator
Yolisa Nalule
Language
English
Country
United States
Format
PDF
Keywords,